The Spanish Flu Pandemic, also know as the
Great Influenza Pandemic, the 1918 Flu Epidemic and La Grippe, was possibly the most devastating epidemic in recorded human history - and a deadly strain of
avian influenza. A viral infection,
it killed some 50 million to
100 million people worldwide in 1918 - 1919. It was caused by the
H1 N1 flu virus. [1]
Note: The current avian flu is H5 N1 - a very different strain.
The Spanish Flu killed more people in 25 weeks than;
• Black Death (Bubonic Plague) in 4 years 1347 - 1351
• The total Nº of people killed in the 5 years of WW1 1914 -18
• The total Nº of people killed from HIV AIDS in the last 25 years. [2]
The Allies of World War 1 frequently called it the
Spanish Flu. This was mainly because the pandemic received greater press coverage in
Spain than the rest of the world, because
Spain was not involved in the war and there was no wartime censorship and was the first to report the epidemic.
Spain did have one the worst early outbreaks of the disease with some
8 million people infected in May 1918 and
King Alfonso XIII of Spain was one of the early victims
In Spain, they called it the "French Flu"
It was also known as
"only the flu" or
"the grippe" by public health officials seeking to prevent panic.
The belligerents squashed news of the outbreak so the enemy will not find out about their weakness.
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Early Records of Influenza
Hippocrates was the first to record an epidemic of flu-like infection in
412 BC when it wiped out the
Athenian army.
[3]
The first recorded
European epidemic was in
1173-1174 although the first generally agreed pandemic occurred in
1580. Since then there have been 31 documented pandemics of cough, shivering, aching

pains and sweating; all symptoms suggestive of flu.
It is impossible to establish the early history of flu as it was so little understood until the
mid 20th century. Also, reparatory infections would have been secondary to other deadly infectious diseases such as
plague, smallpox, typhus and
measles.
There were two pandemics in the 19th century,
1847-48 and
1889.
The 20th century had 4 pandemics in;
1918, [H1N1] Spanish flu;
1957 [H2N2] Asian flu (70,000 deaths) [4] 1968 [H3N2] Hong Kong Flu (34,000 deaths); and
1977 [H5N1] [5]
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Why was the 1918 Spanish Flu the deadliest?
All flu viruses are thought to have originated in birds. Scientists also think that to cause human epidemics, the virus had to jump from birds to pigs, where the genetic changes occur to enable the strains to spread in mammals (humans).

Different influenza strains spread around the world annually. Every so often, a strain tough enough to kill millions emerges. Experts believe the world is overdue for another pandemic. Unravelling what made the
1918 Spanish flu so vicious could help doctors' better react if a similar strain returns.
Asia's current bird flu, a strain known as
H5N1, clearly can jump from poultry to people. Most cases have been traced directly to contact with sick birds, although
human-to-human transmission has not been ruled out in some instances.
New research by scientists using
lung samples preserved from victims of the 1918 flu, a

llowed the reconstruction of the
hemagglutinin protein, present on the surface of the
flu virus,

which allows it to attach to and penetrate lung cells.
Hemagglutinin from
human and
bird flu viruses interact with different cell receptors,
which is why birds infecting people is rare.
However, the new studies show the structure of the
hemagglutinin from the
1918 flu changed to make it capable of attaching to human cells. In doing so, it retained the features found in
avian viruses, not human or pig strains.
The
hemagglutinin from the
1918 virus is in a different family, called
H1, than the
H5 bird flu affecting the world today. Leading British investigator,
Sir John Skehel said
"The two are quite different", meaning the research will not have an immediate impact on today's
bird flu. [6]
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The Most Deadly for the 20 to 40's
Influenza is usually a killer of the elderly and young children.
However, the Spanish Flu was most deadly for people aged 20 to 40's. This is thought to have occurred because the immune system of the young and elderly is weakened and cannot easily fight the virus.
People aged 20 to 40 are in the prime of life. Their bodies reacted, or in fact
over-reacted, to the unknown
1918 virus, causing the lungs to fill with blood from burst blood vessels and in fact
death was by drowning in one's own bodily fluids.
After-the-fact surveys of bloodstream antibodies suggest that 98% of Americans alive in 1918 and 1919 had been infected
The
flu virus had a profound virulence, with a
mortality rate in the USA of 2.5% compared to the previous flu epidemics which were less than 0.1%
(25 times higher) Different regions suffered different mortality rates
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The First Recorded Case
The first true victim or the
1918 Spanish Flu has been lost to history. Some experts believe the virus originated in
China- birthplace of many flu strains.
Shortly before breakfast on Monday,
11 March 1918 the first recorded case of Spanish Flu occurred

when
Company cook Albert Gitchell reported to the infirmary at
Camp Funston, Fort Riley, Kansas.He complained of a "bad cold". Immediately behind him came
Corporal Lee W Drake with a similar complaint.
By noon,
Camp Surgeon Edward R Schreiner had over 100 sick men on his hands, all apparently suffering the same symptoms.
[7]
Within five weeks, 1,127 people would be infected and 46 would die.
Fort Riley was a sprawling establishment housing 26,000 men within its 20,000-acre boundaries. The winters were bone-chilling cold - the summers sweltering. Sandwiched between these two extremes were blinding dust storms.
Within the camp were thousands of horses and mules that produced a stifling 9 tons of manure each month. Disposal of the manure was by burning, often made more unpleasant by the driving wind.
Like most army camps, it bred its own swine and poultry for consumption.

In April and May soldiers at
Camps Hancock, Lewis and
Sherman came down with the same ailment. Over 500 prisoners at
San Quentin, California also fell ill. Influenza spreading among men living in close quarters did not alarm public health officials at the time. Little data existed to indicate any sizable spread among the civilian population.
Besides, the nation had bigger matters on its mind - it had a war to win!
In March 84,000 American 'Dough-boys' set out for
Europe. They were followed by another
118,000 in April 1918. Little did they know they were carrying with them a virus more deadly than the rifles they carried. While sailing the Atlantic, the 15th US Cavalry incurred
36 cases of influenza, resulting in
6 deaths. By May, the killer flu had established itself on 2 continents and was spreading spectacularly.
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The
influenza of 1918 showed no bias in its approach to the combatants in World War I. Men from all sides sickened and died.
Great Britain reported 31,000 flu cases in June alone. By early summer, the flu had spread beyond the
U.S. and
Western Europe.
Numerous cases were reported in
Russia, North & South Africa, South America and
India- which suffered one of the worst mortality rates with
over 17 million dying after infected troop ships returned home.
The
Pacific Ocean provided no protection as influenza spread to parts of
China, Japan (with one of the lowest mortality rates), the
Philippines, Australia and
New Zealand.By July, the
Spanish Flu of 1918 had
infected millions and tens of thousands had already died. This first wave was but a prelude.
During the autumn, it would mutate and reappear in full devastating force.
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1918 Time line in the USA
March : First reported case at
Camp Funston, Kansas. News of the war dominates headlines and after a few weeks, the flu epidemic abates and most Americans believe the worst is over.
April to June : Thousands of infected American troops pass through the east coast exit ports and sail to the fighting in
Europe. When they land in
France, the virus spreads across the continent, infecting hundreds of thousands of civilians and combatants alike.
July : Public health officials issue a bulletin about the so-called
Spanish Influenza.
August : The second wave of the virus mutates hits
Europe hard. Troop and supply ships spread the disease. Sailors stationed on board the Receiving Ship in
Boston Harbour begin reporting sick with flu-like symptoms on the 27th. By August 30th over 60 sailors were sick. Flu sufferers commonly described feeling as if they "had been beaten all over with a club." Within 2 weeks over 2,000 officers and men of the First Naval District had contracted influenza.
In the latter part of August 1918, somewhere in western France, the virus mutates and becomes highly toxic.
September :
Dr Victor Vaughn acting
Surgeon General of the Army, proceeds to
Camp Devens 
near
Boston. What
Vaughn sees changes his life forever:
"I saw hundreds of young stalwart men in uniform coming into the wards of the hospital. Every bed was full, yet others crowded in. The faces wore a bluish cast; a cough brought up blood stained sputum. In the morning the dead bodies are stacked outside like cordwood." On the day,
Vaughn arrived at
Camp Devens,
63 men died from influenza.
Vaughn, a former president of the
American Medical Association, stated,
"This infection, like war, kills the young, vigorous, robust adults. The husky male either made a speedy and rather abrupt recovery or was likely to die." He stated that the world was lucky the
'Spanish Lady' hadn't claimed even more victims. He pointed out that doctors of the day
"knew no more about flu than the 14th century Florentines had known about Black Death".
The Navy Radio School at
Harvard University in Cambridge reports the
first cases of flu among 5,000 young men studying radio communications.
On September 5 the
Massachusetts Department of Health alerts area newspapers that an epidemic is underway.
US Surgeon General Rupert Blue dispatches advice to the press on

how to recognise the influenza symptoms.
Blue prescribed bed rest, good food, salts of quinine and aspirin for the sick.
Bayer Aspirin was just introduced to the US market at the time of the Spanish flu. But because Bayer was a German company, many Americans distrusted it and thought it was a form of germ warfare. Ironically, one of the fatal flu victims was Anton Dilger, in charge of German biological warfare in WW 1
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Lt. Col. Philip Doane, head of the
Health & Sanitation Section of the Emergency Fleet Corporation, speaking in
Washington DC, fuels the rumour and speculation by blaming the
Germans for the deadly influenza that was striking
Americans.
"It would be quite easy for one of those German agents to turn loose Spanish influenza germs in a theatre or some other place where large numbers of persons are assembled. The Germans have started epidemics in Europe and there is no reason why they should be particularly gentle with America." said Doane.
Dr William Hassler,
Chief of San Francisco's Board of Health, predicts
Spanish flu will not reach the city. On 24th September
Edward Wagner, a Chicagoan newly settled in
San Francisco,

falls ill with
influenza.
On 28th September, 200,000 gather in
Philadelphia for a
4th Liberty Loan Drive. Days after the parade,
635 new cases of influenza were reported. Within days, the city was forced to admit that epidemic conditions exits.
Churches, schools and theatres are ordered closed.
Royal Copeland, the
Health Commissioner of New York announces,
"The city is in no danger of an epidemic. No need for our people to worry."
October :
Boston registers
202 deaths from
Spanish flu on 2nd October. The city cancels its Liberty Bond parades and sporting events.
Churches were closed and the stock market was put on half-days.
On October 6th Philadelphia posts the first of several gruesome records for the month:
289 influenza related deaths in a single day.

Congress approves a special
US$1 million fund to enable the
US Public Health Service to recruit physicians and nurses to deal with the growing epidemic.
US Surgeon General Rupert Blue sets out to hire over 1,000 doctors and 700 nurses. Many medical professionals are already engaged in providing care to fighting soldiers.
Blue was forced to look for recruits in old-age homes and rehabilitation centres.
851 New Yorkers die from Spanish flu in a single day. In
Philadelphia, the city's death rate for one single week is
700 times higher than normal.
The crime rate in
Chicago drops by 43%. Authorities attribute the drop to the toll that
influenza was taking on the city's potential lawbreakers.
October 1918 turns out to be the deadliest month in the nation's history as 195,000 Americans fall victim to influenza. The total of Americans killed in its 25-week rampage would be 675,000 [8]
November : To mark the end of
World War 1, 30,000
San Franciscans take to the streets to celebrate. There was much dancing and singing.
Everyone wore a face mask.
Sirens wail on November 21, signalling to
San Franciscans that it is safe - and legal - to remove their protective face masks. At that point
2,122 were dead from
influenza.
December : 5,000 new cases of
influenza were reported in
San Francisco [9]
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Case Studies
New Zealand Expeditionary Force: As in the
SARS epidemic,
(SARS is also causes by a virus)some outbreaks of
Spanish flu can be traced to a single person. A transport carrying 1,150 troops from
New Zealand anchored off
Freetown, Sierra Leone. Influenza was raging on shore and on some
British warships nearby.
Unwisely a conference of ship's captains was called on one of them.
The captain of the
New Zealand Expeditionary Force transport sat next to the
captain of the warship. The former did not suffer from influenza subsequently, although he felt rather 'off colour' for a few days following. There had been absolutely no contact between shore and the transport, although some provisions were delivered to the ship's side.
Influenza began when the ship was about four days out and increased quickly in violence until practically all of the soldiers were infected.
[10]
In all, there were 900 serious cases and 83 deaths.
Brevig Mission, Alaska had a population of 84 in 1918. In November 1918, it lost 85% of its population to
Spanish flu leaving only 13 children and teenagers.
In February 1998, The
Molecular Pathology Division of the US Armed Forces Institute of Pathology recovered samples of the
1918 influenza from a frozen corpse of an
Inuit woman buried almost eight decades in the permafrost at Brevig. This was one of four recovered samples containing
viable genetic material of the 1918 virus. This sample provided scientists a unique opportunity to study the virus and determine it was
avian flu H1N1.
Samoan Islands in the Pacific Ocean were split between the
United States, which controlled the

eastern islands, and
New Zealand, which had seized the western islands from
Germany at the start of the World War. On 17th November 1918, the
steamship Talune, from
New Zealand, anchored at
Apia, the capital of
Western Samoa.
It carried people ill with flu. Before the end of that year, a matter of
less than two months, 7,542 died of influenza and its complications in
Western Samoa,
approximately 20% of the total population. [11]
Without orders from the government but based on what he learned from a radio news service, the
Governor of American Samoa, Navy Cmdr. John M Poyer, instituted a quarantine policy. When he head of the outbreak on
Western Samoa, he banned travel to or from the neighbouring islands,

which were about 60 kilometres apart. When the
Governor of Western Samoa, Lt Col. Robert Logan, sent a boat with mail to
American Samoa to be put on the itinerant mail boat docked there,
Poyer refused even to allow the bags to be transferred.
Enraged, Logan temporarily stopped all radio communication with the American islands.
Poyer persuaded the island's natives to mount a shore patrol to prevent illegal landings. People who disembarked from ships sailing from the
American mainland were kept under house arrest for a specified period or examined daily.
Aspects of the quarantine continued into 1920, a year after Poyer departed to the sound of a 17-gun salute.
There were no influenza deaths in American Samoa
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Social Facts
Many cities states and countries enforced restrictions on public gatherings and travel to try to minimise the epidemic. In many places,
theatres, dance halls, churches and other public gathering places, were shut down for a year.
Quarantines were enforced with little success
(except for American Samoa - see above, and Iceland).Some communities placed armed guards at the borders and turned back or quarantined any travellers.
One US town even outlawed shaking hands
(in hindsight a wise move).
Some communities closed all stores or required customers not to enter, but place their orders outside the store for filling. There were many reports of places with no health care workers to tend the sick because of their own ill health and
no able-bodied morticians or gravediggers. Mass graves were dug by steam shovel and bodies buried without coffins in many places.
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<
Notable Victims 
The following people died in the epidemic:
• Guillaume Apollinaire,
French surrealist poet .
• Felix Arndt,
American composer
• Randolph Bourne,
American political thinker
• Henry G Ginaca,
American inventor
• Myrtle Gonzalez,
American actress
• Joe Hall,
Canadian ice hocky player
• Phoebe Hurst,
American educator
• Hans E Lau,
Danish astronomer
• Harold Lockwood,
American actor
• King Watzke,
New Orleans bandleader
• Reggie Schwarz,
South African cricketer
• Yakov Sverdlov,
Russian revolutionary
• Jacinta and Francisco Marto , 2 of the 3 visionaries at Fatima, Portugal 1917
• William Walker,
British diver
• Anton Dilger,
in charge of German biological warfare in WWI
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US President Woodrow Wilson became sick with flu in early 1919 while negotiating the crucial Treaty of Versailles to end the World War [ 12]
Conclusion:
The
Spanish flu was unusual in killing mostly many young and health adults, as opposed to more common influenzas that cause most mortality among newborn and the old and infirm.
People without symptoms could be struck suddenly and rendered too feeble to walk within hours.
Many would die the next day.
Symptoms included a blue tint to the face and coughing up blood caused by sever obstruction the lungs. In further stages, the virus caused an uncontrollable haemorrhaging that filled the lungs.
Patients would drown in their own body fluids.
Global mortality rate from the influenza was estimated at 2.5% - 5%. The disease spread across the world killing up to 50 million people in 25 weeks. Some estimates put the total killed at over twice that number,
possibly as high as 100 million. An estimated 17 million died in
India alone, with a mortality rate of 5% of the population.
In the Indian Army almost 22% of troops who caught it died
Some
200,000 were killed in
Britain and more than
400,000 in
France. The death rate was especially high in indigenous people, where
some entire villages in Alaska and southern Africa perished.
Fourteen percent of the population of Fiji Islands died in a period of only 2 weeks. By July 1919 257,363 deaths in
Japan were attributed to
influenza, giving a mortality rate of only 0.425%, much lower than all other Asian countries for which data is available.
On 5th October 2005, researchers announced the genetic sequence of the 1918 flu strain had been reconstructed using tissue samples. The 2005 H5N1 bird flu strain spreading through Asia has some features of the 1918 strain but so far is not able to pass easily from human to human [13]
At some point in late 1919, on a day as lost to history as the one of its emergence, Spanish flu made a final human being ill - then mutated again and disappeared
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Reviewed on 20 January 2013